Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics

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DOIResolve DOI: http://doi.org/10.1007/s11060-015-1899-6
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TypeArticle
Journal titleJournal of Neuro-Oncology
ISSN0167-594X
Volume125
Issue1
Pages91102; # of pages: 12
Subjectaconitic acid; adenosine; alanine; arginine; choline; citric acid; creatine; glucose; glutamic acid; glutamine; glutathione; glycerophosphate; histidine; inositol; isocitric acid; isoleucine; leucine; lomeguatrib; methionine; methylated DNA protein cysteine methyltransferase; phosphorylcholine; proline; serine; succinic acid; taurine; temozolomide; threonine; tryptophan; unindexed drug; valine; amino acid metabolism; antineoplastic activity; cancer cell line; cancer resistance; cell viability; citric acid cycle; concentration response; controlled study; cytotoxicity; down regulation; drug sensitivity; enzyme inhibition; genetic transcription; glioblastoma; glioblastoma multiforme cell line; glycolysis; human cell; human tissue; metabolite; metabolomics; primary tumor; upregulation
Abstract
Publication date
PublisherSpringer International Publishing
LanguageEnglish
AffiliationNational Research Council Canada; Information and Communication Technologies
Peer reviewedYes
NPARC number21276985
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Record identifierf46dfba2-3983-4ffd-8307-a73e2c6cb594
Record created2015-11-10
Record modified2016-05-09
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