Production of α2,6-sialylated IgG1 in CHO cells

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DOIResolve DOI: http://doi.org/10.1080/19420862.2015.1029215
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TypeArticle
Journal titlemAbs
ISSN1942-0862
1942-0870
Volume7
Issue3
Pages571583; # of pages: 13
SubjectB4GALT1; CHO cells; ECL, Erythrina Cristagalli lectin; GT, β1,4-galactosyltransferase 1; HILIC, hydrophilic interaction liquid chromatography; IgG1; LC-ESI-MS, liquid chromatography coupled to electrospray ionization mass spectrometry; MAL-II, Maackia Amurensis lectin II; N-glycosylation; PEI, polyethylenimine; SIAT1; SNA, Sambucus Nigra agglutinin; ST6, α2,6-sialyltransferase 1; TZM, trastuzumab (Herceptin®); cIEF, capillary zone electrophoresis isoelectric focusing; mAbs, monoclonal antibodies; sialylation; transfection; α2,3SA, α2,3-linked sialic acid; α2,6SA, α2,6-linked sialic acid
Abstract
Publication date
PublisherTaylor & Francis Group
LanguageEnglish
AffiliationHuman Health Therapeutics; National Research Council Canada
Peer reviewedYes
NRC numberNRC-HHT-53284
NPARC number21275405
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Record identifiere6369b2f-f442-4fe0-96b1-6e446ebe188f
Record created2015-07-08
Record modified2016-05-09
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