The development and assessment of high-throughput mass spectrometry-based methods for the quantification of a nanoparticle drug delivery agent in cellular lysate

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DOIResolve DOI: http://doi.org/10.1002/jms.3444
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TypeArticle
Journal titleJournal of Mass Spectrometry
ISSN1076-5174
Volume49
Issue11
Pages11711180; # of pages: 10
SubjectChromatography; Desorption; Gene transfer; Ionization; Ionization of liquids; Liquids; Matrix algebra; Spectrometry; Surface active agents; Throughput; Tissue culture; Desorption electrospray ionization; Fast chromatography; Gemini surfactant; Matrix assisted laser desorption ionization; Electrospray ionization; lipid; n,n bis(dimethylhexadecyl) 1,3 propane diammonium; nanoparticle; surfactant; cell extract; analytic method; cell interaction; cell lysate; collisionally activated dissociation; controlled study; intermethod comparison; mass spectrometry; matrix assisted laser desorption ionization time of flight mass spectrometry; qualitative analysis; quantitative analysis; tandem mass spectrometry; tissue culture; cell line; drug delivery system; genetic transfection; high throughput screening; liquid chromatography; metabolism; reproducibility; sensitivity and specificity; statistical model; Linear Models; Pharmaceutical Preparations
Abstract
Publication date
PublisherWiley
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC)
Peer reviewedYes
NPARC number21275446
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Record identifier85a9f48d-0663-40e2-98ca-d607d080148a
Record created2015-07-14
Record modified2016-05-09
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