Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells

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DOIResolve DOI: http://doi.org/10.1002/biot.201500176
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TypeArticle
Journal titleBiotechnology Journal
ISSN1860-6768
Volume11
Issue2
Pages290297; # of pages: 8
SubjectBioreactors; Body fluids; DNA; Gene therapy; Mammals; Manufacture; Productivity; Viruses; Adeno-associated virus; Bioprocess optimization; HEK293T; ICELLis; Manufacturing strategy; Recombinant adeno-associated virus; Stirred tank bioreactors; Volumetric productivity; Vectors
Abstract
Publication date
PublisherWiley
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC)
Peer reviewedYes
NPARC number21277505
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Record identifier155978b4-5776-493c-9910-871683b2cd98
Record created2016-03-09
Record modified2016-05-09
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