DOI | Resolve DOI: https://doi.org/10.1107/S0365110X60001308 |
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Author | Search for: Kartha, G.1; Search for: Ahmed, F.R.1; Search for: Barnes, W.H.1 |
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Affiliation | - National Research Council of Canada
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Format | Text, Article |
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Abstract | The structure of the hydrochloride DL-alphaprodine has been determined by the isomorphous replacement method with the aid of data for the hydrobromide. Zero-level normal, and first-level generalized, projections along the three axes have been employed. The structure has been refined by three-dimensional Fourier and differential syntheses. The stereochemical configuration found for the alphaprodine molecule agrees with that of one of four possible isomers and confirms that proposed by Beckett and co-workers on conformational and other grounds. The piperidine ring has the chair form with the phenyl ring equatorial and the propionoxy chain axial; the methyl group on C(3) is trans to the phenyl ring on C(4). |
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Publication date | 1960 |
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In | |
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Note | Addendum to this paper available in Acta Crystallographica, Volume 14 (1), January 1961. (NRCC 6054). |
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Language | English |
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Peer reviewed | Yes |
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NRC number | NRCC 5621 |
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NPARC number | 21274957 |
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Export citation | Export as RIS |
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Report a correction | Report a correction (opens in a new tab) |
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Record identifier | 06d0e467-7a5a-43c2-8b73-9adc5c347317 |
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Record created | 2015-05-04 |
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Record modified | 2020-03-12 |
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