Ecotoxicological assessment of a high energetic and insensitive munitions compound : 2,4-Dinitroanisole (DNAN)

Par Conseil national de recherches du Canada

DOI	Trouver le DOI : https://doi.org/10.1016/j.jhazmat.2013.08.043
Auteur	Rechercher : Dodard, Sabine G.¹; Rechercher : Sarrazin, Manon¹; Rechercher : Hawari, Jalal¹; Rechercher : Paquet, Louise¹; Rechercher : Ampleman, Guy; Rechercher : Thiboutot, Sonia; Rechercher : Sunahara, Geoffrey I.¹
Affiliation	Conseil national de recherches du Canada. Développement des cultures et des ressources aquatiques
Format	Texte, Article
Sujet	2 ,4 ,6-trinitrotoluene; 2 ,4-dinitroanisole; Ecotoxicity; Ecotoxicological assessment; Environmental risk assessment; Experimental conditions; Microtox; Pseudokirchneriella subcapitata; Algae; Ammunition; Aromatic compounds; Environmental impact; Explosives; Risk assessment; Toxicity; 2,4 dinitroanisole; aromatic nitro compound; nitrobenzene derivative; unclassified drug; bacterium; bioluminescence; concentration (composition); decision making; dose-response relationship; earthworm; ecotoxicology; environmental impact; environmental risk; grass; green alga; risk assessment; toxicity test; trinitrotoluene; algal growth; avoidance behavior; bioavailability; bioluminescence; biotransformation; concentration response; earthworm; ecotoxicity; Eisenia andrei; environmental impact; fluid balance; growth inhibition; oxidative phosphorylation; perennial ryegrass; Pseudokirchneriella subcapitata; Vibrio fischeri
Résumé	The high explosive nitroaromatic 2,4-dinitroanisole (DNAN) is less shock sensitive than 2,4,6-trinitrotoluene (TNT), and is proposed as a TNT replacement for melt-cast formulations. Before using DNAN in munitions and potentially leading to environmental impact, the present study examines the ecotoxicity of DNAN using selected organisms. In water, DNAN decreased green algae Pseudokirchneriella subcapitata growth (EC50=4.0mg/L), and bacteria Vibrio fischeri bioluminescence (Microtox, EC50=60.3mg/L). In soil, DNAN decreased perennial ryegrass Lolium perenne growth (EC50=7mg/kg), and is lethal to earthworms Eisenia andrei (LC50=47mg/kg). At sub-lethal concentrations, DNAN caused an avoidance response (EC50=31mg/kg) by earthworms. The presence of DNAN and 2-amino-4-nitroanisole in earthworms and plants suggested a role of these compounds in DNAN toxicity. Toxicity of DNAN was compared to TNT, tested under the same experimental conditions. These analyses showed that DNAN was equally, or even less deleterious to organism health than TNT, depending on the species and toxicity test. The present studies provide baseline toxicity data to increase the understanding of the environmental impact of DNAN, and assist science-based decision makers for improved management of potential DNAN contaminated sites. © 2013.
Date de publication	2013-08-23
Dans	Journal of Hazardous Materials 262 (23 août 2013) : 143–150.
Langue	anglais
Publications évaluées par des pairs	Oui
Numéro du CNRC	NRCC 55573
Numéro NPARC	21269865
Exporter la notice	Exporter en format RIS
Signaler une correction	Signaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement	d2998754-2cb7-4801-9ff5-a510027642f8
Enregistrement créé	2013-12-13
Enregistrement modifié	2020-04-22

Date de modification :: 2024-04-20