Animal models

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DOI	Trouver le DOI : https://doi.org/10.1258/0007142001903238
Auteur	Rechercher : Small, D.; Rechercher : Buchan, A.
Format	Texte, Article
Sujet	acute cerebrovascular accidents; cerebrovascular accident; cerebral ischemia; lacunar infarction; ischemic stroke; animal model
Résumé	Animal models of cerebral ischaemia mimic at best less than 25% od all strokes. Compounds which prove efficacious in animal models should, therefore, only be expected to imporve outcome in a quarter of all strokes. If trials for acute stroke are to succeed, stroke subgroups represented by the animal models should be targeted. For the other subgroups, e.g. lacunar stroke, appropriate animal models need to be deveoloped. Moreover, throbolysis should be included in animal models because it is likely to be used as a first line treatment for ischaemic stroke and any future therapeutics with need to be compatible with it.
Date de publication	2000-01-01
Maison d’édition	Oxford University Press
Dans	British Medical Bulletin 56, nº 2 : 307–317.
Langue	anglais
Publications évaluées par des pairs	Oui
Numéro NPARC	9367434
Exporter la notice	Exporter en format RIS
Signaler une correction	Signaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement	c409218f-0d0c-4413-8f66-15add90014fe
Enregistrement créé	2009-07-10
Enregistrement modifié	2020-05-27