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Gouvernement du Canada / Government of Canada

Recherche

Drosophila innate immunity and response to fungal infections

Par Conseil national de recherches du Canada

DOITrouver le DOI : https://doi.org/10.1111/j.1462-5822.2008.01120.x
AuteurRechercher : ; Rechercher : 1
Affiliation
  1. Conseil national de recherches du Canada. Institut de recherche en biotechnologie du CNRC
FormatTexte, Article
SujetAdult; Cell Line; Drosophila; Drosophila melanogaster; genetics; pharmaceutical
Résumé
The fruit fly Drosophila melanogaster is an important model for the analysis of the interaction between host immune systems and fungal pathogens. Recent experiments have extended our understanding of the Toll-based signalling pathway critical to response to fungal infections, and identified new elements involved in cellular and humoral-based defences. The fly immune system shows remarkable sophistication in its ability to discriminate among pathogens, and the powerful genetics available to researchers studying the adult fly response, and the ability to manipulate cultured phagocytic cell lines with RNAi, are allowing researchers to dissect the molecular details of the process
Date de publication
Langueanglais
Numéro du CNRC49547
Numéro NPARC3538893
Exporter la noticeExporter en format RIS
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Identificateur de l’enregistrementbe1ff259-05dd-44d2-96d4-b9ee9aca97c4
Enregistrement créé2009-03-01
Enregistrement modifié2020-04-15
Date de modification :