Téléchargement | - Voir le manuscrit accepté : Development of a MRI phantom to emulate the relaxation times of the neonatal brain at 3 Tesla (PDF, 540 Kio)
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Auteur | Rechercher : Orr, T.N.; Rechercher : Gelman, N.; Rechercher : Winter, J.; Rechercher : Campbell, G.1; Rechercher : Thompson, R.T. |
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Affiliation | - Conseil national de recherches du Canada. Institut des matériaux industriels du CNRC
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Format | Texte, Article |
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Conférence | 15th Scientific Meeting and Exhibition, International Society for Magnetic Resonance in Medicine, May 19-25, Berlin Germany |
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Résumé | Prematurity greatly increases the risk of neurological impairment in newborn infants. Magnetic resonance imaging (MRI) provides powerful techniques for non-invasively investigating the impact of premature birth on early brain development. Experimental testing of MRI techniques on human nenonates is not ethically appropriate. Our previous work has shown that techniques used for brain imaging in adults are not optimal for neonates. Therefore, there is a crucial need for phantoms that can mimic MRI properties of the neonatal brain. Polyvinyl alcohol cryogel (PVA-C) has been investigated as a MRI phantom material for the adult brain. Our previous work showed that MRI relaxation times (T1 and T2) of 6-15% PVA-C were lower than those reported for neonatal white matter at 2.30 Tesla. The objective of this study was to investigate the relationship between PVA-C relation times and temperature to determine if sufficiently long relaxation times could be obtained by increasing temperature. |
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Date de publication | 2007 |
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Dans | |
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Langue | anglais |
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Publications évaluées par des pairs | Oui |
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Numéro NPARC | 21274310 |
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Exporter la notice | Exporter en format RIS |
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Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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Identificateur de l’enregistrement | 96c53db6-bff3-4389-8739-25f797943f2d |
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Enregistrement créé | 2015-03-09 |
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Enregistrement modifié | 2020-06-04 |
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