| Téléchargement | - Voir le manuscrit accepté : An MRI-based semiquantitative index for the evaluation of brain atrophy and lesions in Alzheimer’s disease, mild cognitive impairment, and normal aging (PDF, 743 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1159/000319537 |
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| Auteur | Rechercher : Chen, Wei1; Rechercher : Song, Xiaowei1; Rechercher : Zhang, Yunting; Rechercher : Darvesh, Sultan; Rechercher : Zhang, Ningnannan1; Rechercher : D'Arcy, Ryan C. N.1; Rechercher : Black, Sandra; Rechercher : Rockwood, Kenneth |
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| Affiliation | - Conseil national de recherches du Canada. Institut du biodiagnostic du CNRC
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| Format | Texte, Article |
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| Sujet | Aging; Alzheimer’s disease; Brain lesions; Brain atrophy; Mild cognitive impairment |
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| Résumé | Background: This study investigates how T1-weighted MRI can be used to evaluate brain anatomical changes. We investigated these changes in Alzheimer’s disease (AD) and normal aging. Methods: A semiquantitative brain atrophy and lesion index (BALI) was constructed by adapting existing visual rating scales and validated in 3 datasets. Results: The T1- and T2-weighted-imaging-based scores were highly correlated. They were both closely associated with age and with cognitive test scores. Conclusion: The T1-based BALI helps describe brain structural variability in AD, mild cognitive impairment and normal aging. |
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| Date de publication | 2010-09-01 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 17673480 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 68962b02-02bc-4445-9886-99b8e867023d |
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| Enregistrement créé | 2011-04-03 |
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| Enregistrement modifié | 2020-04-17 |
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