Téléchargement | - Voir le manuscrit accepté : A comparison of methods using optical coherence tomography to detect demineralized regions in teeth (PDF, 1.7 Mio)
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DOI | Trouver le DOI : https://doi.org/10.1002/jbio.201100014 |
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Auteur | Rechercher : Sowa, Michael G.1; Rechercher : Popescu, Dan P.1; Rechercher : Friesen, Jeri R.1; Rechercher : Hewko, Mark D.1; Rechercher : Choo-Smith, Lin-P'ing1 |
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Affiliation | - Conseil national de recherches du Canada. Institut du biodiagnostic du CNRC
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Format | Texte, Article |
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Sujet | Enamel demineralization; diagnostic discrimination; incipient caries detection; optical coherence tomography; lognormal fit; support vector machine classification |
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Résumé | Optical coherence tomography (OCT) is a three-dimensional optical imaging technique that can be used to identify areas of early caries formation in dental enamel. The OCT signal at 850 nm back-reflected from sound enamel is attenuated stronger than the signal back-reflected from demineralized regions. To quantify this observation, the OCT signal as a function of depth into the enamel (also known as the A-scan intensity), the histogram of the A-scan intensities and three summary parameters derived from the A-scan are defined and their diagnostic potential compared. A total of 754 OCT A-scans were analyzed. The three summary parameters derived from the A-scans, the OCT attenuation coefficient as well as the mean and standard deviation of the lognormal fit to the histogram of the A-scan ensemble show statistically significant differences (p < 0.01) when comparing parameters from sound enamel and caries. Furthermore, these parameters only show a modest correlation. Based on the area under the curve (AUC) of the receiver operating characteristics (ROC) plot, the OCT attenuation coefficient shows higher discriminatory capacity (AUC = 0.98) compared to the parameters derived from the lognormal fit to the histogram of the A-scan. However, direct analysis of the A-scans or the histogram of A-scan intensities using linear support vector machine classification shows diagnostic discrimination (AUC = 0.96) comparable to that achieved using the attenuation coefficient. These findings suggest that either direct analysis of the A-scan, its intensity histogram or the attenuation coefficient derived from the descending slope of the OCT A-scan have high capacity to discriminate between regions of caries and sound enamel. |
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Date de publication | 2011-07-25 |
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Dans | |
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Langue | anglais |
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Publications évaluées par des pairs | Oui |
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Numéro NPARC | 19726592 |
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Exporter la notice | Exporter en format RIS |
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Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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Identificateur de l’enregistrement | 4ff23780-c600-4a5c-8044-0050e0b6afa4 |
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Enregistrement créé | 2012-03-28 |
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Enregistrement modifié | 2020-04-21 |
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