DOI | Trouver le DOI : https://doi.org/10.1007/978-3-642-21822-4_10 |
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Auteur | Rechercher : Paquet, Eric1; Rechercher : Viktor, Herna L. |
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Affiliation | - Conseil national de recherches du Canada
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Format | Texte, Chapitre de livre |
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Conférence | 24th International Conference on Industrial Engineering and Other Applications of Applied Intelligent Systems (IEA/AIE 2011), June 28-July 1 2011, Syracuse, New York, USA |
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Sujet | 3D; amino acid sequences; multi-modal; retrieval; shape; unexpectedness; amino acids; indexing (of information); industrial engineering; intelligent systems; systems analysis; topology; proteins |
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Résumé | Complex systems, such as proteins, are inherently difficult to describe, analyse and interpret. A multimodal methodology which utilizes various diverse representations is needed to further our understanding of such intrinsically multifaceted systems. This paper presents a multimodal system designed to describe and interpret the content of the Protein Data Bank, a repository which contains tens of thousands of known proteins. We describe how complimentary modalities based on the amino acid sequence, the protein's backbone (or topology) and the envelope (the outer shape), are used when furthering our understanding of proteins' functionalities, behaviours and interactions. We illustrate our methodology against the human haemoglobin and show that the interplay between modalities allows our system to find unexpected, complimentary results with different domains of validity. © 2011 Springer-Verlag. |
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Date de publication | 2011 |
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Maison d’édition | Springer Berlin Heidelberg |
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Dans | |
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Série | |
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Langue | anglais |
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Publications évaluées par des pairs | Oui |
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Numéro NPARC | 21271604 |
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Exporter la notice | Exporter en format RIS |
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Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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Identificateur de l’enregistrement | 381c2ec9-1be0-4c3e-a95a-02c35e320fec |
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Enregistrement créé | 2014-03-24 |
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Enregistrement modifié | 2020-03-03 |
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