| DOI | Trouver le DOI : https://doi.org/10.1002/0471142735.im1914s93 |
|---|
| Auteur | Rechercher : Conlan, J. Wayne1; Rechercher : Chen, Wangxue1; Rechercher : Bosio, Catharine M.; Rechercher : Cowley, Siobhán C.; Rechercher : Elkins, Karen L. |
|---|
| Affiliation | - Conseil national de recherches du Canada. Institut des sciences biologiques du CNRC
|
|---|
| Format | Texte, Article |
|---|
| Sujet | animal anatomy; bacteremia; bacterial skin disease; cytology; disease model; external ear; Francisella tularensis; gastrointestinal tract; immunological procedures; immunology; methodology; microbiological examination; microbiology; mouse; mouse strain; pathogenicity; peritoneal cavity; respiratory tract infection; skeletal muscle; tularemia; animal structures; bacteremia; bacteriological techniques; disease models, animal; ear auricle; Francisella tularensis; gastrointestinal tract; immunologic techniques; mice; mice, inbred strains; muscle, skeletal; peritoneal cavity; respiratory tract infections; skin diseases, bacterial; tularemia |
|---|
| Résumé | This unit describes the utility of various mouse models of infection for studying pathogenesis and adaptive immune responses to the facultative intracellular bacteria pathogen Francisella tularensis. By judicious use of different combinations of mouse and bacterial strains, as well as different routes of infection, murine tularemia models may be used to explore a complete picture of F. tularensis infection and immunity. Moreover, studies using Francisella, particularly the Live Vaccine Strain (LVS), serve as a convenient and tractable model system that appears to be representative of mammalian host responses to intracellular pathogens in general. |
|---|
| Date de publication | 2011-04-01 |
|---|
| Maison d’édition | John Wiley & Sons, Inc |
|---|
| Dans | |
|---|
| Langue | anglais |
|---|
| Publications évaluées par des pairs | Oui |
|---|
| Numéro NPARC | 21271327 |
|---|
| Exporter la notice | Exporter en format RIS |
|---|
| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
|---|
| Identificateur de l’enregistrement | 314cde20-499e-4a6e-8995-01bcfcbcc748 |
|---|
| Enregistrement créé | 2014-03-24 |
|---|
| Enregistrement modifié | 2021-04-13 |
|---|
