Superoxide, amine buffers and tetranitromethane: A novel free radical chain reaction

DOI	Trouver le DOI : https://doi.org/10.1080/10715760000301081
Auteur	Rechercher : Hodges, G.R.¹; Rechercher : Ingold, K. U.¹
Affiliation	Conseil national de recherches du Canada
Format	Texte, Article
Sujet	amine; free radical; superoxide; tetranitromethane; aqueous solution; chemical reaction; chemical structure; oxidative stress; pH; reaction analysis; buffers; free Radicals; HEPES; morpholines; oxidation-reduction; superoxides; tetranitromethane
Résumé	The amine buffer Tris slowly reduces tetranitromethane (TNM) to the nitroform anion in a non-accelerating reaction. The amine buffers HEPES and MOPS also (slowly) react with TNM but the dialkylaminoalkyl radicals formed from these two buffers undergo further reactions resulting in a rapid, accelerating, free radical chain process whereby the amine is oxidized and TNM reduced. The chemical functionality in any reaction component, not necessarily the buffer, required for this radical chain mechanism is >N-CH<. In the presence of such groups, the quantification of superoxide by TNM is impossible.
Date de publication	2000
Dans	Free Radical Research 33, nº 5 (2000) : 547–550.
Langue	anglais
Publications évaluées par des pairs	Oui
Numéro NPARC	21276779
Exporter la notice	Exporter en format RIS
Signaler une correction	Signaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement	22411902-b736-4ae1-a1c5-6c08bce26bef
Enregistrement créé	2015-10-13
Enregistrement modifié	2020-03-26