| DOI | Trouver le DOI : https://doi.org/10.1016/S0009-8981(01)00796-3 |
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| Auteur | Rechercher : Sowa, Michael G.1; Rechercher : Matas, Anna1; Rechercher : Schattka, Bernhard J.1; Rechercher : Mantsch, Henry H.1 |
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| Affiliation | - Conseil national de recherches du Canada. Institut du biodiagnostic du CNRC
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| Format | Texte, Article |
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| Sujet | In vivo spectroscopy; Skin perfusion; Tissue oxygenation; Pressure ulcers; Blanch response; Projection operators |
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| Résumé | Background: For individuals with lightly pigmented skin, early stage pressure ulcers appear as areas of redness, which have compromised microcirculation and do not blanch in response to pressure. The lack of a visible blanch (hemodynamic response) to pressure is a convenient diagnostic test for stage I sores. However, the blanch response is not visually apparent in people with highly pigmented skin color due to the overwhelming contribution of melanin to the reflectance of skin. Methods: A simple least squares projection operator method is described, which can separate the reflectance contributions from melanin and hemoglobin. The methodology was tested in a study population of 20 subjects with healthy skin. The study population was evenly divided into a lightly pigmented skin group (visible blanch response) and a highly pigmented skin group (no visible blanch response). Results: The hemodynamic response to pressure being applied to the skin could clearly be distinguished spectroscopically in both groups at a high level of statistical significance. Conclusion: The specific aim of this work was directed towards developing a spectroscopic basis for distinguishing the healthy blanch response in a manner that was independent of skin pigmentation. However, the technique has a general application when optical hemodynamic measurements are being made over a diverse patient population or under conditions of varying pigmentation such as the seasonal changes in skin color. |
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| Date de publication | 2002 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro du CNRC | 1944 |
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| Numéro NPARC | 9148021 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 170eb1e7-cc32-469c-a7fe-e7d3fe7012f4 |
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| Enregistrement créé | 2009-06-25 |
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| Enregistrement modifié | 2020-03-30 |
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