Fabrication of titanium/fluorapatite composites and in vitro behavior in simulated body fluid

  1. Get@NRC: Fabrication of titanium/fluorapatite composites and in vitro behavior in simulated body fluid (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1016/j.jmst.2013.01.013
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Journal titleJournal of Materials Science and Technology
Pages523532; # of pages: 10
SubjectBiological environments; Carbonated apatite; Fluorapatites; In-vitro; In-vitro bioactivity; Induced nucleation; Simulated body fluids; Surface conditions; Bioactivity; Calcium carbonate; Fluorine; Phosphorus compounds; Powder metallurgy; Titanium; Sintering
AbstractTitanium/fluorapatite (Ti/FA) composites with various FA additions were fabricated by powder metallurgy. The decomposition of FA during sintering was accelerated by the presence of Ti. The main reaction products of FA and Ti were identified as CaO, Ti phosphides, and CaTiO3. The addition of FA significantly inhibited the densification of Ti. The in vitro bioactivity of the composites was evaluated in a simulated body fluid (SBF). After immersion into the SBF, all the Ti/FA composites induced nucleation and growth of bone-like carbonated apatite on the surface. Co-precipitation of CaCO3 and Mg(OH)2 was also detected on the surface of the composite with high FA addition at an early stage of immersion. Furthermore, the release of fluorine ions from the composite was confirmed, which could promote bone regeneration and retard the formation of caries in the biological environment. The in vitro behavior was attributed to multiple factors, including the surface conditions and the constituents of the composite. The results demonstrated that the Ti/FA composites were bioactive in nature even with a low FA addition and they could introduce the benefit of fluorine ions in the service. © 2013.
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AffiliationNational Research Council Canada (NRC-CNRC); NRC Industrial Materials Institute (IMI-IMI)
Peer reviewedYes
NPARC number21269811
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Record identifierf702fbbb-3f96-4fb5-9256-14b7e9a23579
Record created2013-12-13
Record modified2016-05-09
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