PHAST: A Fast Phage Search Tool

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Journal titleNucleic Acids Research
IssueSUPPL. 2
Subjectaccuracy; article; bacteriophage; client server application; computer graphics; computer program; controlled study; DNA sequence; GenBank; gene cluster; Internet; open reading frame; predictive value; priority journal; prophage; protein analysis; search engine; sensitivity and specificity; sequence database; sequence homology; Databases, Genetic; Genome, Bacterial; Internet; Molecular Sequence Annotation; Prophages; Sequence Analysis, DNA; Software; Bacteria (microorganisms)
AbstractPHAge Search Tool (PHAST) is a web server designed to rapidly and accurately identify, annotate and graphically display prophage sequences within bacterial genomes or plasmids. It accepts either raw DNA sequence data or partially annotated GenBank formatted data and rapidly performs a number of database comparisons as well as phage 'cornerstone' feature identification steps to locate, annotate and display prophage sequences and prophage features. Relative to other prophage identification tools, PHAST is up to 40 times faster and up to 15 more sensitive. It is also able to process and annotate both raw DNA sequence data and Genbank files, provide richly annotated tables on prophage features and prophage 'quality' and distinguish between intact and incomplete prophage. PHAST also generates downloadable, high quality, interactive graphics that display all identified prophage components in both circular and linear genomic views. PHAST is available at ( © 2011 The Author(s).
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AffiliationNational Research Council Canada (NRC-CNRC); National Institute for Nanotechnology (NINT-INNT)
Peer reviewedYes
NPARC number21271535
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Record identifierf4eed25d-c4d4-4c89-ab4c-3d7e5ec82f75
Record created2014-03-24
Record modified2016-05-09
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