DOI | Resolve DOI: https://doi.org/10.1038/nrn2995 |
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Author | Search for: Neuwelt, Edward A.; Search for: Bauer, Björn; Search for: Fahlke, Christoph; Search for: Fricker, Gert; Search for: Iadecola, Constantino; Search for: Janigro, Damir; Search for: Leybaert, Luc; Search for: Molnár, Zoltán; Search for: O’Donnell, Martha E.; Search for: Povlishock, John T.; Search for: Saunders, Norman R.; Search for: Sharp, Frank; Search for: Stanimirovic, Danica1; Search for: Watts, Ryan J.; Search for: Drewes, Lester R. |
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Affiliation | - National Research Council of Canada. NRC Institute for Biological Sciences
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Format | Text, Article |
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Subject | blood–brain barrier; neuroscience; brain barrier sciences |
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Abstract | The delivery of many potentially therapeutic and diagnostic compounds to specific areas of the brain is restricted by brain barriers, of which the most well known are the blood–brain barrier (BBB) and the blood–cerebrospinal fluid (CSF) barrier. Recent studies have shown numerous additional roles of these barriers, including an involvement in neurodevelopment, in the control of cerebral blood flow, and — when barrier integrity is impaired — in the pathology of many common CNS disorders such as Alzheimer's disease, Parkinson's disease and stroke. |
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Publication date | 2011-03 |
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In | |
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Language | English |
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Peer reviewed | Yes |
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NPARC number | 19739546 |
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Export citation | Export as RIS |
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Report a correction | Report a correction (opens in a new tab) |
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Record identifier | f1ad24d3-2a1b-43d4-877c-149ecee13aef |
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Record created | 2012-04-19 |
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Record modified | 2020-04-21 |
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