Bone remodeling in a new biomimetic polymer-composite hip stem

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Journal titleJournal of Biomedical Materials Research Part A
Pages164174; # of pages: 11
Subjectbiomimetic hip composite stem; internal bone remodeling; strain energy density; total hip replacement; finite element method
AbstractAdaptive bone remodeling is an important factor that leads to bone resorption in the surroudning femoral bone and implant loosening. Taking into account this factor in the design of hip implants is of clinical importance, since it allows the prediction of the bone-density redistribution and enables the monitoring of bone adaptation after prosthetic implantation. In this paper adaptive bone remodeling around a new biomimetic polymer-composite based (CF/PA12) hip prosthesis is investigated in order to evaluate the amount of stress shielding and bone resorption. The design concept of this new prosthesis is based on a hollow sub-structure made of hydroxyapatite-coated, continuous carbon fiber (BF) reinforced polyamide 12 (PA12) composite with an internal soft polymer-based core. Strain energy density theory coupled with 3-D Finite Element models are used to predict bone desity redistributions in the femoral bone before and after total hip replacement using both polymer-composite and titanium stems. The result of numerical simulations of bone remodeling revealed that the CF-PA12 composite stem generates an excellent bone density pattern compared to the titanium-based stem, indicating the effectiveness of the composite stem to reduce bone resorption caused by stress shielding phenomenon. This may result in an extended lifetime of Total Hip Replacement (THR).
Publication date
PublisherWiley Periodicals, Inc.
Copyright noticeMaterial in this document is covered by the provisions of the Copyright Act, by Canadian laws, policies, regulations and international agreements. Such provisions serve to identify the information source and, in specific instances, to prohibit reproduction of materials without written permission.
AffiliationNRC Industrial Materials Institute (IMI-IMI); National Research Council Canada
Access conditionavailable
Peer reviewedYes
NRC number50619
NPARC number11213129
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Record identifierf13efda9-86f5-4837-88cd-92dd5841c111
Record created2009-10-03
Record modified2016-05-09
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