Download | - View accepted manuscript: A new tool to assess ceramide bioactivity: 6-bromo-7-hydroxycoumarinyl-caged ceramide (PDF, 685 KiB)
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DOI | Resolve DOI: https://doi.org/10.1039/C1CC12345A |
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Author | Search for: Young, Ah Kim; Search for: Carter Ramirez, Daniel M.1; Search for: Costain, Willard J.2; Search for: Johnston, Linda J.1; Search for: Bittman, Robert |
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Affiliation | - National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
- National Research Council of Canada. NRC Institute for Biological Sciences
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Format | Text, Article |
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Abstract | The bioactivity of natural, long-chain ceramides has until now been studied after its delivery to cells in organic solvent mixtures containing dodecane. We have synthesized ceramides conjugated to a (6-bromo-7-hydroxycoumarin-4-yl)methyl group. The photocaged ceramide is efficiently released with 350 nm light in aqueous solution at neutral pH, thus providing a promising new tool to study ceramide's properties. |
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Publication date | 2011-07-15 |
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In | |
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Language | English |
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Peer reviewed | Yes |
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NPARC number | 19649703 |
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Export citation | Export as RIS |
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Report a correction | Report a correction (opens in a new tab) |
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Record identifier | dd9cd129-0ebd-4fb8-ae89-c54392e657f8 |
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Record created | 2012-03-28 |
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Record modified | 2020-04-21 |
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