Vibrational spectroscopy applications in clinical chemistry

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TypeBook Chapter
Book titleVibrational Spectroscopy Applications in Clinical Chemistry : Applications in Life, Pharmaceutical and Natural Sciences
Series titleHandbook of Vibrational Spectroscopy; Volume 5
Subjectserum; blood; urine; amniotic fluid; PLS; analysis; quantification; glucose; urea; lipids
AbstractVibrational spectroscopy is well suited in principle to carry out several of the most common quantitative blood, serum, and urine tests. In addition, the same techniques can serve as the foundation for explicitly diagnostic tests, with the vibrational spectrum serving as a molecular fingerprint characterizing the sample of interest; to the extent that the spectrum changes in a characteristic way with disease onset and progression; it may be exploited as a marker of both. This article summarizes the techniques that might be applied to carry out these tests routinely in the clinical laboratory, and detailing specific analytical and diagnostic tests that have been established as proof-of-concept examples to illustrate the potential for this approach.
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PublisherJohn Wiley & Sons, Ltd
AffiliationNational Research Council Canada
Peer reviewedYes
NRC number1877
NPARC number9742729
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Record identifier99896383-ea1b-4f7e-a7d6-e8dcde782b63
Record created2009-07-17
Record modified2016-09-28
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