A literature review of the numerical analysis of abdominal aortic aneurysms treated with endovascular stent grafts

  1. Get@NRC: A literature review of the numerical analysis of abdominal aortic aneurysms treated with endovascular stent grafts (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1155/2012/820389
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Journal titleComputational and Mathematical Methods in Medicine
Article number820389
Subjectabdominal aorta aneurysm; aneurysm rupture; aorta wall; artery calcification; artery compliance; biomechanics; blood flow; blood rheology; endovascular aneurysm repair; finite element analysis; laminar flow; mathematical computing; mathematical model; review; shear stress; stress strain relationship; virtual reality; viscoelasticity; Young modulus; aorta; biological model; blood vessel; blood vessel transplantation; calcinosis; catheter; computer simulation; flow kinetics; hemodynamics; human; instrumentation; mechanical stress; methodology; pathology; risk; stent; theoretical model; Aorta; Aortic Aneurysm, Abdominal; Biomechanics; Blood Vessel Prosthesis Implantation; Blood Vessels; Calcinosis; Catheters; Computer Simulation; Finite Element Analysis; Hemodynamics; Humans; Models, Cardiovascular; Models, Theoretical; Rheology; Risk; Stents; Stress, Mechanical
AbstractThe purpose of this paper is to present the basic principles and relevant advances in the computational modeling of abdominal aortic aneurysms and endovascular aneurysm repair, providing the community with up-to-date state of the art in terms of numerical analysis and biomechanics. Frameworks describing the mechanical behavior of the aortic wall already exist. However, intraluminal thrombus nonhomogeneous structure and porosity still need to be well characterized. Also, although the morphology and mechanical properties of calcifications have been investigated, their effects on wall stresses remain controversial. Computational fluid dynamics usually assumes a rigid artery wall, whereas fluid-structure interaction accounts for artery compliance but is still challenging since arteries and blood have similar densities. We discuss alternatives to fluid-structure interaction based on dynamic medical images that address patient-specific hemodynamics and geometries. We describe initial stresses, elastic boundary conditions, and statistical strength for rupture risk assessment. Special emphasis is accorded to workflow development, from the conversion of medical images into finite element models, to the simulation of catheter-aorta interactions and stent-graft deployment. Our purpose is also to elaborate the key ingredients leading to virtual stenting and endovascular repair planning that could improve the procedure and stent-grafts. © 2012 David Roy et al.
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AffiliationNational Research Council Canada (NRC-CNRC); NRC Industrial Materials Institute (IMI-IMI)
Peer reviewedYes
NPARC number21269437
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Record identifier938ff2bb-ba27-491a-bdf6-91a91786726d
Record created2013-12-12
Record modified2016-05-09
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