Glycoanalysis of Bacterial Glycome

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EditorSearch for: Mander, Lew; Search for: Liu, Hung-Wen; Search for: Wong, Chi-Huey; Search for: Wang, Peng George
Journal titleComprehensive Natural Products II, Chemistry and Biology
Series titleCarbohydrates, Nucleosides and Nucleic Acids; Volume 6
Pages157173; # of pages: 17
AbstractBacterial glycomes and their associated metabolic and carbohydrate processing enzymes critical for virulence expression are identified and exploited as targets for drug discovery, glyco-engineering, vaccine design, and diagnosis of disease. Mass spectrometry (MS) in combination with modern separation techniques is one of the most powerful and versatile techniques for the structural analysis and characterization of carbohydrate interactions in microbial virulence. Owing to recent developments in MS, the profiling of glycans enables the characterization of bacterial glycomes, further advances in MS technologies are anticipated to contribute to glycomics. This chapter outlines the current development and applications of MS for bacterial glycomics studies.
Publication date
PublisherElsevier Science
AffiliationNational Research Council Canada; NRC Institute for Biological Sciences
Peer reviewedYes
NPARC number17400942
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Record identifier6c749c22-86e0-4259-84bf-dba0f86e598a
Record created2011-03-25
Record modified2016-05-09
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