Computational Sequence Design Techniques for DNA Microarray Technologies

  1. (PDF, 869 KB)
DOIResolve DOI:
AuthorSearch for: ; Search for: ; Search for:
TypeBook Chapter
Book titleSystematic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances
Pages# of pages: 30
AbstractIn systems biology and biomedical research, microarray technology is a method of choice that enables the complete quantitative and qualitative ascertainment of gene expression patterns for whole genomes. The selection of high quality oligonucleotide sequences that behave consistently across multiple experiments is a key step in the design, fabrication and experimental performance of DNA microarrays. The aim of this chapter is to outline recent algorithmic developments in microarray probe design, evaluate existing probe sequences used in commercial arrays, and suggest methodologies that have the potential to improve on existing design techniques.
Publication date
AffiliationNRC Institute for Information Technology; National Research Council Canada
Peer reviewedYes
NPARC number18608248
Export citationExport as RIS
Report a correctionReport a correction
Record identifier63fcb134-6145-4d1f-b1bc-a10ac6ac7a19
Record created2011-09-21
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)
Date modified: