Selective inhibition of USP7

  1. Get@NRC: Selective inhibition of USP7 (Opens in a new window)
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Journal titleChemistry & Biology
Pages437438; # of pages: 2
AbstractThe deubiquitinating enzyme USP7 is an emerging oncology and antiviral target. Reverdy et al., in this issue of Chemistry & Biology, disclose the first small-molecule inhibitor selective for USP7, which recapitulates its knockdown in cancer cells and hence demonstrates the therapeutic feasibility of USP7 inhibitors.
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AffiliationNRC Biotechnology Research Institute; National Research Council Canada
Peer reviewedYes
NRC number53180
NPARC number20548175
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Record identifier4cd66c2d-8ff5-4c33-843d-3876f7ce0c8e
Record created2012-08-28
Record modified2016-05-09
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