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Selective inhibition of USP7

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1016/j.chembiol.2012.04.001
AuthorSearch for: 1; Search for: 1
Affiliation
  1. National Research Council of Canada. NRC Biotechnology Research Institute
FormatText, Article
Abstract
The deubiquitinating enzyme USP7 is an emerging oncology and antiviral target. Reverdy et al., in this issue of Chemistry & Biology, disclose the first small-molecule inhibitor selective for USP7, which recapitulates its knockdown in cancer cells and hence demonstrates the therapeutic feasibility of USP7 inhibitors.
Publication date
In
  • Chemistry & Biology 19, no. 4 (20 April 2012): 437–438.
LanguageEnglish
Peer reviewedYes
NRC numberNRCC 53180
NPARC number20548175
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Record identifier4cd66c2d-8ff5-4c33-843d-3876f7ce0c8e
Record created2012-08-28
Record modified2020-04-21
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