State-related changes in MEG functional connectivity reveal the task-positive sensorimotor network

  1. Get@NRC: State-related changes in MEG functional connectivity reveal the task-positive sensorimotor network (Opens in a new window)
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Journal titlePLoS ONE
Article numbere48682
Subjectadult; anatomical variation; article; beta rhythm; brain function; electroencephalogram; female; frontal eye field; functional assessment; gamma rhythm; human; human experiment; image analysis; image display; magnetoencephalography; male; motor performance; neuroimaging; normal human; prefrontal cortex; rest; sensorimotor function; task performance; visual feedback; Adult; Brain; Brain Mapping; Cues; Female; Humans; Magnetoencephalography; Male; Nerve Net; Psychomotor Performance; Reproducibility of Results; Rest; Visual Perception; Young Adult
AbstractFunctional connectivity measures applied to magnetoencephalography (MEG) data have the capacity to elucidate neuronal networks. However, the task-related modulation of these measures is essential to identifying the functional relevance of the identified network. In this study, we provide evidence for the efficacy of measuring "state-related" (i.e., task vs. rest) changes in MEG functional connectivity for revealing a sensorimotor network. We investigate changes in functional connectivity, measured as cortico-cortical coherence (CCC), between rest blocks and the performance of a visually directed motor task in a healthy cohort. Task-positive changes in CCC were interpreted in the context of any concomitant modulations in spectral power. Task-related increases in whole-head CCC relative to the resting state were identified between areas established as part of the sensorimotor network as well as frontal eye fields and prefrontal cortices, predominantly in the beta and gamma frequency bands. This study provides evidence for the use of MEG to identify task-specific functionally connected sensorimotor networks in a non-invasive, patient friendly manner. © 2012 Bardouille, Boe.
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AffiliationNational Research Council Canada (NRC-CNRC); Medical Devices (MD-DM)
Peer reviewedYes
NPARC number21269202
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Record identifier404ba69f-1e3f-4f3d-87f7-84b2ca9a3ba5
Record created2013-12-12
Record modified2016-05-09
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