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Spatial resolution of ultrasound-modulated optical tomography used for the detection of absorbing and scattering objects in thick scattering media

From National Research Council Canada

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DOIResolve DOI: https://doi.org/10.1117/12.841828
AuthorSearch for: 1; Search for: 1; Search for: 1
Affiliation
  1. National Research Council of Canada. NRC Industrial Materials Institute
FormatText, Article
ConferenceSPIE Photonics West 2010, January 23-28, 2010, San Francisco, California, USA
Abstract
Ultrasound-modulated optical tomography (UOT) combines the spatial resolution of ultrasonic waves and the spectroscopic properties of light to detect optically absorbing and/or scattering objects in highly scattering media. In this work, a double-pass confocal Fabry-Perot interferometer is used as a bandpass filter to selectively detect the ultrasoundtagged photons. The limited etendue of the confocal Fabry-Perot interferometer is compensated by using a singlefrequency laser emitting high-peak-power optical pulses. Compared to photoacoustic tomography, UOT is not only sensitive to optical absorption but also to scattering properties. In this paper, we consider the detection of absorbing and scattering objects embedded in thick (30 to 60 mm) tissue-mimicking phantoms and biological tissues. The experimental evaluation of the spatial resolution of the technique is compared to that expected from the ultrasonic beam intensity profile. Preliminary results indicate that the edge spread function is influenced by the level of absorption of the embedded object.
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In
  • Proceedings of SPIE 75642A (23 January 2010).
LanguageEnglish
Peer reviewedYes
NRC numberNRCC 52439
NPARC number14521133
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Record identifier1a926627-6130-44f3-ba3a-c04b84473e93
Record created2010-03-01
Record modified2020-04-17
Date modified: